Effect of methylprednisolone and "pulse" therapy with methylprednisolone sodium succinate on autologous immune complex nephritis in rats.
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منابع مشابه
Recurrent High-Dose Intravenous Methylprednisolone Succinate Pulse Therapy-Induced Hepatopathy in a Patient with Multiple Sclerosis
Objective: We describe recurrent and reversible hepatopathy in a girl with multiple sclerosis (MS) after glucocorticoid pulse therapy, to point out the possibility that glucocorticoid may harm the liver. Clinical Presentation and Intervention: An 11-year-old girl with MS, who was treated with high-dose methylprednisolone succinate pulse therapy, developed elevation of liver enzymes. The episode...
متن کاملRecurrent high-dose intravenous methylprednisolone succinate pulse therapy-induced hepatopathy in a patient with multiple sclerosis.
OBJECTIVE We describe recurrent and reversible hepatopathy in a girl with multiple sclerosis (MS) after glucocorticoid pulse therapy, to point out the possibility that glucocorticoid may harm the liver. CLINICAL PRESENTATION AND INTERVENTION An 11-year-old girl with MS, who was treated with high-dose methylprednisolone succinate pulse therapy, developed elevation of liver enzymes. The episode...
متن کاملMega-dose methylprednisolone versus pulse methylprednisolone.
Although the main hematologic findings, such as spherocytosis, polychromasia, anisopoikilocytosis, and reticulocytosis, etc. and Coombs test results were not given, the patient most likely had hemolytic anemia, for which he was given pulse methylprednisolone (MP) three days after intravenous immunoglobulin (IVIG) therapy, which might also cause encephalopathy. However, the hematologic changes w...
متن کاملRecurrent High-Dose Intravenous Methylprednisolone Succinate Pulse Therapy-Induced Hepatopathy in a Patient with Multiple Sclerosis
Objective: We describe recurrent and reversible hepatopathy in a girl with multiple sclerosis (MS) after glucocorticoid pulse therapy, to point out the possibility that glucocorticoid may harm the liver. Clinical Presentation and Intervention: An 11-year-old girl with MS, who was treated with high-dose methylprednisolone succinate pulse therapy, developed elevation of liver enzymes. The episode...
متن کاملThe effect of methylprednisolone sodium succinate on erythrocyte and haemoglobin function.
1. As it has been suggested that the beneficial effect of methylprednisolone in shock is due to its effect on erythraocyte oxygen affinity, we studied its effect on incubated erythrocytes and on haemoglobin solution. 2. Incubation of fresh whole blood anticoagulated with acid/citrate/dextrose with methylprednisolone (7 mmol/l) produced a significant decrease in oxygen affinity, which was not se...
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ژورنال
عنوان ژورنال: Journal of Pharmacobio-Dynamics
سال: 1980
ISSN: 0386-846X,1881-1353
DOI: 10.1248/bpb1978.3.117